Amlodipine Besylate 5 MG Tablets - Usage, Side Effects, Substitutes, Composition And More | Libre (2023)

Amlodipine Besylate 5 MG Tablet is used for treatmentangina,high bloodpressureand coronary heart disease. It is recommended just in casecardiac arrestif other medicines don't work. Amlodipine Besylate 5 MG tablet is the main ingredient of this medicine. Increases myocardial oxygenation in patients with vasospastic angina.

Amlodipine Besilate 5 mg tablet belongs to the class of calcium channel blockers that inhibit the entry of calcium ions into the slow channels of the smooth muscle of blood vessels and the myocardium during depolarization. This leads to relaxation of coronary smooth muscle and coronary vasodilation.

The medicine should be taken according to the dose stated on the prescription. Drug overdose can lead to complications. Depending on the effects the drug has on the patient, the doctor may make variations in the dose.

The drug may not be safe to use duringpregnancyor breastfeeding. The dosage should be low for the elderly and people with diabeteslives the problems. If you have heart problems, taking Amlodipine Besilate 5 mg Tablets may make your health problems worse.

Primary cardiac symptoms of calcium blocker overdose are hypotension and bradycardia. Hypotension is caused by peripheral vasodilation, myocardial depression and bradycardia. Bradycardia is a consequence of sinus bradycardia, second or third degree atrioventricular block, or sinus arrest with junctional rhythm.

Intraventricular conduction is usually unaffected, so QRS duration is normal (verapamil prolongs P-R interval and bepridil prolongs Q-T and may cause ventricular arrhythmias including torsade de pointes).

In several reported cases, overdose with calcium channel blockers has been associated with hypotension and bradycardia, which was initially resistant to atropine but became more sensitive to this agent when higher doses were administered (approximately 1 gram per hour for more than 24 hours).

The most common uses of this medicine are:

• Hypertension

• angina pektoris

• Allergies

• Cardiogene shock

The following are some of the common side effects that may occur:

• Edema peripheral

• Redness

• palpitations

• Headache

  See Also

  Amlodipin AWD 5 mg Tabletten – Wirkung, Nebenwirkungen, Dosierung

• Rash

• itch

• Sexual dysfunction

• Nausea

• Stomach ache

• Dyspepsia

• Gingival hyperplasia

• Muscle cramps

• Weakness

• shortness of breath

• Hypotension

• Syncope

• Insomnia

• Weight gain

• Flatulence

• Jail

• Dizziness

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• Hives

• Spanning

• Gastritis

• How long does the effect last?

  This effect of this medicine lasts for about 24 hours.

• What is the beginning of action?

  The maximum effect of this medicine can be seen after 6 to 12 hours.

• Are There Pregnancy Warnings?

  In small animals, teratogenic and embryotoxic effects have been demonstrated. No well-controlled studies have been conducted in pregnant women. Use during pregnancy only if absolutely necessary and if the benefit outweighs the potential risk to the foetus.

• Forming a habit?

  No habit formation tendency was noted.

• Are There Breastfeeding Warnings?

  There are no clear data on the use of this medicine in nursing mothers. This medicine should only be used if absolutely necessary and there is no other safer alternative.

• Does it affect liver function?

  In case of liver damage dose adjustment is required.

• Does it affect kidney function?

  No relevant information available.

Below is a list of medicines that have the same composition, strength and shape as Amlodipine Besilate 5 MG tablets and can therefore be used as a substitute.

• Avacard 5 mg tabletten

  Ranbaxy Laboratories Ltd

• Amlosafe 5 mg tabletten

  Aristo Pharmaceuticals Pvt.Ltd

• Amtas 5 MG-tablet

  Intas Pharmaceuticals Ltd

• Amlodac 5 mg-tablet

  Zydus Cadila

• Nicardia 30MG tablets SR

  Jb Chemie

• Instructions for the missed dose

  The missed dose should be taken as soon as possible. It is recommended to skip the missed dose if it is already time for the next scheduled dose.

• Are there instructions for overdose?

  Seek urgent medical attention or consult a doctor in case of overdose.

Amlodipine Besylate 5 MG Tablet works by inhibiting the entry of calcium ions into "slow channels" or selected voltage-sensitive areas of vascular smooth muscle and myocardium during depolarization, causing relaxation of coronary vascular smooth muscle and coronary vasodilation; increases myocardial oxygenation in patients with vasospastic angina.

Anytime you take more than one drug or mix it with a particular food or drink, you run the risk of drug interactions.

• Interaction with alcohol

  Alcohol consumption should be avoided while taking this medicine, especially at the beginning of taking the medicine or when changing the dose. Symptoms such as headache, dizziness, changes in heart rate or heart rate should be reported to the doctor.

• Interaction with lab test

  No information available.

• Drug interaction

  carbamazepine

  The desired effect of Amlodipine Besylate 5 mg Tablets is not achieved when it is taken together with carbamazepine. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.

  dexamethasone

  The desired effect of Amlodipine Besylate 5 mg Tablets is not achieved when it is taken together with dexamethasone. This interaction is more likely if dexamethasone is taken for more than a week. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.

  itraconazole

  Itraconazole can increase the concentration of amlodipine besylate 5 mg tablets and can cause serious side effects such as fluid retention, irregular heart rhythm and low blood pressure. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.

  Rifampicin

  The desired effect of Amlodipine Besilate 5 mg tablets is not achieved when it is taken together with Rifampic. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.

• Interaction with disease

  Hypotension

  Amlodipine Besilate 5mg Tablet is not recommended in patients suffering from hypotension or cardiogenic shock as it further lowers blood pressure. Increased angina pectoris and/or myocardial infarction occurred with the initiation or titration of the calcium channel blocker dose. Beware of severe aortic stenosis. Use with caution in patients with severe hepatic impairment. Safety and effectiveness in children have not been established. Dose titration should be performed after 7-14 days of the given dose.

• Interaction with food

  Consumption of grapefruit juice is not recommended as it increases the concentration of amlodipine besylate 5 mg tablets. Notify the doctor if you experience dizziness, headache, swelling of the hands and feet.