Amlodipine Besylate 5 MG Tablet is used for treatmentangina,high bloodpressureand coronary heart disease. It is recommended just in casecardiac arrestif other medicines don't work. Amlodipine Besylate 5 MG tablet is the main ingredient of this medicine. Increases myocardial oxygenation in patients with vasospastic angina.
Amlodipine Besilate 5 mg tablet belongs to the class of calcium channel blockers that inhibit the entry of calcium ions into the slow channels of the smooth muscle of blood vessels and the myocardium during depolarization. This leads to relaxation of coronary smooth muscle and coronary vasodilation.
The medicine should be taken according to the dose stated on the prescription. Drug overdose can lead to complications. Depending on the effects the drug has on the patient, the doctor may make variations in the dose.
The drug may not be safe to use duringpregnancyor breastfeeding. The dosage should be low for the elderly and people with diabeteslives the problems. If you have heart problems, taking Amlodipine Besilate 5 mg Tablets may make your health problems worse.
Primary cardiac symptoms of calcium blocker overdose are hypotension and bradycardia. Hypotension is caused by peripheral vasodilation, myocardial depression and bradycardia. Bradycardia is a consequence of sinus bradycardia, second or third degree atrioventricular block, or sinus arrest with junctional rhythm.
Intraventricular conduction is usually unaffected, so QRS duration is normal (verapamil prolongs P-R interval and bepridil prolongs Q-T and may cause ventricular arrhythmias including torsade de pointes).
In several reported cases, overdose with calcium channel blockers has been associated with hypotension and bradycardia, which was initially resistant to atropine but became more sensitive to this agent when higher doses were administered (approximately 1 gram per hour for more than 24 hours).
The most common uses of this medicine are:
The following are some of the common side effects that may occur:
shortness of breath
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How long does the effect last?This effect of this medicine lasts for about 24 hours.
What is the beginning of action?The maximum effect of this medicine can be seen after 6 to 12 hours.
Are There Pregnancy Warnings?In small animals, teratogenic and embryotoxic effects have been demonstrated. No well-controlled studies have been conducted in pregnant women. Use during pregnancy only if absolutely necessary and if the benefit outweighs the potential risk to the foetus.
Forming a habit?No habit formation tendency was noted.
Are There Breastfeeding Warnings?There are no clear data on the use of this medicine in nursing mothers. This medicine should only be used if absolutely necessary and there is no other safer alternative.
Does it affect liver function?In case of liver damage dose adjustment is required.
Does it affect kidney function?No relevant information available.
Below is a list of medicines that have the same composition, strength and shape as Amlodipine Besilate 5 MG tablets and can therefore be used as a substitute.
Avacard 5 mg tablettenRanbaxy Laboratories Ltd
Amlosafe 5 mg tablettenAristo Pharmaceuticals Pvt.Ltd
Amtas 5 MG-tabletIntas Pharmaceuticals Ltd
Amlodac 5 mg-tabletZydus Cadila
Nicardia 30MG tablets SRJb Chemie
Instructions for the missed doseThe missed dose should be taken as soon as possible. It is recommended to skip the missed dose if it is already time for the next scheduled dose.
Are there instructions for overdose?Seek urgent medical attention or consult a doctor in case of overdose.
Amlodipine Besylate 5 MG Tablet works by inhibiting the entry of calcium ions into "slow channels" or selected voltage-sensitive areas of vascular smooth muscle and myocardium during depolarization, causing relaxation of coronary vascular smooth muscle and coronary vasodilation; increases myocardial oxygenation in patients with vasospastic angina.
Anytime you take more than one drug or mix it with a particular food or drink, you run the risk of drug interactions.
Interaction with alcoholAlcohol consumption should be avoided while taking this medicine, especially at the beginning of taking the medicine or when changing the dose. Symptoms such as headache, dizziness, changes in heart rate or heart rate should be reported to the doctor.
Interaction with lab testNo information available.
carbamazepineThe desired effect of Amlodipine Besylate 5 mg Tablets is not achieved when it is taken together with carbamazepine. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.
dexamethasoneThe desired effect of Amlodipine Besylate 5 mg Tablets is not achieved when it is taken together with dexamethasone. This interaction is more likely if dexamethasone is taken for more than a week. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.
itraconazoleItraconazole can increase the concentration of amlodipine besylate 5 mg tablets and can cause serious side effects such as fluid retention, irregular heart rhythm and low blood pressure. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.
RifampicinThe desired effect of Amlodipine Besilate 5 mg tablets is not achieved when it is taken together with Rifampic. Tell your doctor if you are taking any of the medicines. Frequent monitoring of blood pressure is necessary. Based on the clinical condition, it is necessary to make an alternative drug or appropriate dose adjustment.
Interaction with disease
HypotensionAmlodipine Besilate 5mg Tablet is not recommended in patients suffering from hypotension or cardiogenic shock as it further lowers blood pressure. Increased angina pectoris and/or myocardial infarction occurred with the initiation or titration of the calcium channel blocker dose. Beware of severe aortic stenosis. Use with caution in patients with severe hepatic impairment. Safety and effectiveness in children have not been established. Dose titration should be performed after 7-14 days of the given dose.
Interaction with foodConsumption of grapefruit juice is not recommended as it increases the concentration of amlodipine besylate 5 mg tablets. Notify the doctor if you experience dizziness, headache, swelling of the hands and feet.
Questions: What is amlodipine besylate 5mg tablets?
Answer:This medicine works by increasing blood flow in the body. It is also used to prevent muscle contraction and coronary atherosclerosis.
Questions: What is the use of amlodipine besylate 5 mg tablet?
Answer:It is used for the treatment and prevention of conditions and symptoms of diseases such as angina pectoris and hypertension.
Q: How long should I take Amlodipine Besylate 5 MG tablet before I notice an improvement in my condition?
Answer:This medicine should be taken until you notice an improvement in your health.
Questions: How often should I take amlodipine besylate 5mg tablet?
Answer:This medicine should be taken in the dose prescribed by the doctor.
Q: Should I take Amlodipine Besilate 5mg tablet on an empty stomach, before or after food?
Answer:This medicine should be taken after meals in the prescribed dose.
Q: What are the storage and disposal instructions for Amlodipine Besylate 5 MG Tablets?
Answer:This medicine should be stored in a cool, dry place and in its original container. Also keep this medicine out of the reach of children.
Q: How long does it take for Amlodipine Besilate 5 MG Tablets to start working?
Answer:It starts working the day you take it. However, it may take weeks to see the full effect. You should continue to take the medicine even if you feel better or if you do not notice a significant difference.
Q: Does amlodipine besylate 5mg tablets cause itching?
Answer:Yes, it can cause itching in some patients, although this is a rare side effect. With severe itching, it is necessary to seek medical help.
Q: Should I take Amlodipine Besilate 5mg tablet in the morning or evening?
Answer:This medicine can be taken at any time of the day. It is usually advised to take it in the morning, but your doctor may also advise you to take it in the evening.
Q: How long should I take amlodipine besylate 5mg tablet?
Answer:Take this medicine for as long as your doctor prescribes. Do not stop taking this medicine without your doctor's permission.
Q: Is Amlodipine Besilate 5 MG Tablets a beta blocker?
Answer:No, this medicine is not a beta blocker. It belongs to a group of medicines known as calcium channel blockers. It helps lower blood pressure by relaxing the blood vessels so that blood can flow easily through the arteries.
Questions: What are the serious side effects of amlodipine besylate 5mg tablet?
Answer:Side effects of this drug include yellowing of the skin, nausea, vomiting, and loss of appetite), pancreatitis (severe stomach pain, nausea, and vomiting), and recurrent chest pain that may indicate a heart attack.
Amlodipine - Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [cited November 23, 2021]. Available from:https://druginfo.nlm.nih.gov/drugportal/name/amlodipin
Amlodipine 5 mg tablets - EMC [Internet]. www.medicines.org.uk. 2018 [cited November 23, 2021]. Available from:https://www.medicines.org.uk/emc/product/6075/smpc
AMLODIPIN - amlodipine besylate tablet - Daily Med [Internet]. dailymed.nlm.nih.gov. 2008 [Cited November 23, 2021]. Available from:https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b
Exemption:The information contained herein is based on our best knowledge and experience and we have done our best to keep it as accurate and up-to-date as possible, but we ask that it is not considered a substitute for professional advice, diagnosis or therapy.
Lybrate is a medium that provides general information about medicines to our public and does not guarantee its accuracy or completeness. Even if no warning is given for a drug or combination, it never means we are claiming that the drug or combination is safe for consumption without proper consultation with an expert.
Lybrate assumes no responsibility for any aspect of the medication or treatment. If you are concerned about your medication, we strongly recommend that you consult your doctor immediately.
There are several other calcium channel blockers which lower blood pressure in the same way as amlodipine. They include nifedipine, felodipine, lacidipine and lercanidipine. There are also 2 other calcium channel blockers, diltiazem and verapamil, that work slightly differently to lower blood pressure.What is a substitute for amlodipine 5mg? ›
Nifedipine, lisinopril, losartan, and carvedilol are some amlodipine alternatives.What are the most common side effects of amlodipine besylate? ›
- swelling of the hands, feet, ankles, or lower legs.
- upset stomach.
- stomach pain.
- dizziness or lightheadedness.
- excessive tiredness.
In addition to the active ingredient, amlodipine besylate, each tablet contains the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, sodium starch glycolate, and magnesium stearate.